Atipsychotics, also known as major
tranquilizers or neuroleptics, are a group of drugs utilized to manage &
treat psychosis, including hallucinations, delusions, disordered thought or
paranoia, majorly in bipolar disorder and schizophrenia treatment. The constant
development of enhanced next-generation products to defeat the unwanted
reactions & adverse effects of the existing products is boosting the
demands for newer drugs. This factor is expected to augment the growth of the
global market.
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Antipsychotics Usage:
These drugs are rapidly being utilized
in the management of non-psychotic disorders as well. Antipsychotics are generally
effective in easing the signs of psychosis in the short-term. The long-term usage
of antipsychotics is related to adverse effects, for example, metabolic
syndrome, involuntary movement disorders, and gynecomastia. These drugs are
also associated with the growing mortality in geriatric population base with
dementia.
Rexulti (brexpiprazole) by Otsuka:
A new antipsychotic drug—Rexulti
(brexpiprazole) tablets—has been approved by the U. S. Food and Drug
Administration (FDA) for the treatment of people suffering from schizophrenia
and also an adjunctive treatment for people suffering from Major Depressive
Disorder (MDD). Brexpiprazole is a once-daily, 2nd generation or atypical oral
antipsychotic that was developed by Otsuka and co-developed by Otsuka and
Lundbeck.
It is presumed to work through a blend
of antagonist activity at serotonin 5-HT2A receptors and partial agonist
activity at dopamine D2 & serotonin 5-HT1A receptors. It also displays high
affinity for these two receptors, as well as for noradrenaline alpha1B/2C
receptors.
Future Market Insights:
The factors such as the introduction
of novel antipsychotic drugs and high investments in the R&D for the
development of even better drugs are expected to augment the growth of the
global market. In addition, the rising efforts taken by the major manufacturers
to expand therapeutic applications of antipsychotic drugs are also projected to
create huge opportunities for the antipsychotics portfolio expansion in near
future, thereby boosting the product demands. Johnson & Johnson; Eli Lilly
& Co.; Bristol-Myers Squibb; and Pfizer, Inc. are some of the major
companies operating in the worldwide antipsychotic drugs market.
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